THE NEUROLOGY

✍️ Neurology: Self-Assessment || Stroke || Part 02 || Dear Neurology Aspirants! Please! Watch the video for Self-Assessment. The assessment video contains 30 questions from the Chapter: Stroke. The video used objective questions from “The Neurology: Self-Assessment & Review" by Dr. Sunil Kumar. Hope! This will help you to manage your time in the examination hall. Best of Luck!

Question: Which of the following is a Histone Deacetylase Inhibitor? Phenytoin Sodium Valproate Carbamazepine Levetiracetam  Histone Deacetylase Inhibitor Histone deacetylase-9 (HDAC9) gene is associated with pathogenesis of large artery ischemic stroke. HDAC9 inhibitor may prevent ischemic stroke. Sodium Valproate is a nonspecific Histone Deacetylase Inhibitor. Sodium Valproate therapy given after ischemic stroke may be associated with reduced recurrent stroke rate. Reference: Brookes RL, Crichton S, Wolfe CD, Yi Q, Li L, Hankey GJ, Rothwell PM, Markus HS. Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack. Stroke. 2018 Jan;49(1):54-61. [Answer is 2. Sodium Valproate]